Manufacturing


Overall:

  1. Strong Scientific Team with 14 Ph.D. Scientists (10 in US and 3 in China) and ~ 60 M.S./B.S. Scientists; Growing rapidly.
  2. Experienced Management Team
  3. 13 Issued US Patents and foreign equivalents

Chiral Quest – US:

  1. 9,000 ft2 Laboratory near Princeton, NJ with modern equipment
  2. Outstanding process chemists from BMS, Wyeth, Schering-Plough and Eisai process groups.

Suzhou Facilities (24,000 M2):




Multi-functional plant suites

  1. Chiral Quest Suzhou has 9 multi-functional plant suites
  2. Each suite is independent and self-contained so as to minimize the cross contamination
  3. Cryogenic reactor, stainless steel (100L ~ 1000L -78°C)
  4. Glass lined reactors (100L~ 2000L)
  5. Stainless steel Centrifuge LP-600
  6. FZG-15 Vacuum Dryer
  7. SZG Double tapered Vacuum drier

Hydrogenation suites with high pressure capability

  1. Magnetic drive Reactors (500L~1000L ):
    Max. pressure rating100 atmospheres and max. temp 100°C
  2. Hastelloy Reactor (100L~1000L):
    Max. pressure rating100 atmospheres and max. temp 100°C
  3. Glass lined reactors (100L~1000L ):
    Max. pressure rating10 atmospheres and max. temp 100°C

 Process Capabilities: 

1.  Experience in Asymmetric Synthesis
  1. Chiral center generation
  2. Chiral pool
  3. Resolution
  4. High Pressure Hydrogenation Scale up
2.  Homogeneous Catalysis
  1. Asymmetric hydrogenation
  2. Heck reaction
  3. Suzuki coupling
3. Cryogenic Reaction

4. Air-sensitive Compounds Handling

  1. Phosphine ligands
  2. Catalysts

Other general reaction types:

  1. Grignard and Butyl lithium reactions
  2. Nitration
  3. Coupling reactions
  4. Bromination and Chlorination
  5. Hofmann rearrangement
  6. Reduction and Oxidation
  7. Acylation, esterification and hydrolysis
  8. Alkylation
  9. Strecker reaction
  10. Heterocycles


 

 




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