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Chiral Quest develops routes for complex intermediates and APIs and manages tech transfer to full-scale manufacturing. Chiral Quest helps its customers improve their operating efficiencies by:

  • shortening the time-line for production of complex APIs
  • developing a scalable process that will provide increasing quantities as clinical trials advance.
  • managing an efficient and cost-effective supply chain for manufacture
  • providing robust QC methods and a strong CMC package

Services and Products:

Process Development
Chiral Quest chemists have many years of process development experience. They rapidly take a ‘lab-scale’ process and develop a practical, scalable process for cost- effective manufacturing.

Contract Manufacturing
Chiral Quest has delivered >15 multi-step, complex manufacturing projects up to 500 kg scale, on-time and on-budget. The product of our process development and kilo-lab service is a technical package ready to tech-transfer to a manufacturing facility for large-scale manufacturing of complex intermediates and.

Complex Chiral Building Blocks & Intermediates
Utilizing the most advanced chiral catalysis and low cost manufacturing, Chiral Quest is providing commercial scale quantities of complex chiral intermediates at competitive prices.

Chiral Catalysts and Screening Service
Chiral Quest has developed an extensive family of chiral catalyst that provide access to a broad array of chiral functionality. We provide catalysts under a simple IP agreement, and provide a screening service that helps our customers develop the most effective chiral process.

Milestones
2000 Founded by Professor Xumu Zhang of Pennsylvania State University to commercialize Chiral Catalysis.
2003 Public Company (OTC BB: VQPH.OB)
2003 Opening of NJ R&D Lab
2005 Opening of China R&D Lab
2005 Commercial Quantities of four asymmetric hydrogenation catalysts are available
2006 Issued 12th US Patent covering asymmetric hydrogenation catalyst technology


Chiral Quest developed a scalable process and delivered 100 kgs of a difficult intermediate under a very tight time-line that allowed our down-stream manufacturing process to remain on-schedule to meet our clinical time-line. We often turn to CQ for our technically challenging and time-line sensitive supply-chain requirements.

Senior Director of Process R&D, Mid-Sized Pharma Company

Chiral Quest has helped us develop several innovative asymmetric hydrogenation processes to existing chiral intermediates that provide significantly improved manufacturing costs.

VP Technology, Large Fine Chemical Manufacturer

Chiral Quest developed an efficient chiral process to our API that was previously being manufactured via an inefficient resolution process. This will provide a tremendous improvement in cost-of-goods.

Senior VP, BioTech Company

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